Bovine papular stomatitis virus encodes a functionally distinct VEGF that binds both VEGFR-1 and VEGFR-2

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Bovine papular stomatitis virus encodes a functionally distinct VEGF that binds both VEGFR-1 and VEGFR-2.

Bovine papular stomatitis virus (BPSV), a member of the genus Parapoxvirus, causes proliferative dermatitis in cattle and humans. Other species of the genus cause similar lesions, the nature of which has been attributed, at least in part, to a viral-encoded vascular endothelial growth factor (VEGF) that induces vascularization and dermal oedema through VEGF receptor-2 (VEGFR-2). The results of ...

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Constitutive expression of VEGF, VEGFR-1, and VEGFR-2 in normal eyes.

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ژورنال

عنوان ژورنال: Journal of General Virology

سال: 2007

ISSN: 0022-1317,1465-2099

DOI: 10.1099/vir.0.82582-0